A goiter is an enlarged thyroid gland. The thyroid gland, located in the front of your neck, makes thyroid hormones. When your thyroid gland is enlarged, it can produce too much, too little, or just enough thyroid hormone.
Thyroid hormones travel from your thyroid gland through the blood to all parts of your body. They control how your body uses food for energy, and help all your organs work well. Thyroid hormones affect your metabolism rate, which means how fast or slow your brain, heart, muscles, liver, and other parts of your body work.
If your metabolism is too fast or too slow, you won’t feel well. For example, if you don’t have enough thyroid hormone and your metabolism slows down, you might feel tired and cold. Or, if you have too much thyroid hormone, you might feel nervous and warm.
The most common cause of goiter outside of the U.S. is a lack of iodine in the diet. Iodine is a substance in food (iodized salt and seafood) that the thyroid uses to make thyroid hormones. However, a lack of iodine is not common in the U.S. because iodine is added to salt and many foods.
You can have a goiter but have no symptoms at all, other than having some swelling at the base of your neck. Some people also may have
In the U.S., the most common causes of swelling are
Less common causes include a hormone made during pregnancy that increases thyroid hormone production, inflammation of the thyroid, or thyroid cancer. A goiter also can be present in a newborn if his or her thyroid gland doesn’t work properly before birth.
Underactive thyroid gland: when the thyroid gland doesn’t make enough thyroid hormone; also called hypothyroidism. When the thyroid is underactive, the body’s metabolism runs too slowly.
Overactive thyroid gland: when the thyroid gland makes too much thyroid hormone; also called hyperthyroidism. When the thyroid is overactive, metabolism runs too quickly.
Hashimoto’s disease (the most common cause of underactive thyroid): when the immune system attacks and damages the thyroid gland; then the damaged gland no longer makes enough thyroid hormone.
Graves’ disease (the most common cause of overactive thyroid): when the immune system attacks the thyroid gland and causes it to make too much thyroid hormone.
Risk factors include
Some medicines also increase the risk of goiter.
A goiter is often found during a physical exam when your doctor feels swelling in your neck. Your doctor also may use other tests to find the cause of the goiter and to see how advanced it is, such as
Treatment depends on the cause of the goiter, its size, and your symptoms. If your goiter is small and your thyroid is making normal amounts of thyroid hormone, your doctor might observe the goiter over time instead of starting treatment right away.
Possible treatments include
Surgery is rarely used. However, removal of the thyroid gland might be recommended for a large goiter, for one causing breathing or swallowing problems, for nodules, or for thyroid cancer.