Examining the Optics of Thyroid Eye Disease

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Thyroid Eye Disease (TED) can also be referred to as Graves’ orbitopathy, Graves’ ophthalmopathy, Graves’ eye disease, thyroid-associated orbitopathy, or thyroid-associated ophthalmopathy. 

In TED, the immune cells that attack the thyroid gland (to cause Graves’ disease) also attack adipose and fibroblast tissues around the eyes. TED, or Graves’ eye disease, is an autoimmune condition that is mainly driven by stimulation of the thyroid-stimulating hormone (TSH) receptor (TSHR). This receptor is mainly located in the thyroid gland but is also found in other tissues in the body such as the tissues around the eyes. The levels of these antibodies can determine the severity and prognosis of TED.

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