Patient Guide
Congenital Adrenal Hyperplasia, also referred to as CAH, is a genetic disorder in which the two adrenal glands do not function properly because of mutations in the gene encoding adrenal steroid 21-hydroxylase, which is an enzyme. Without this enzyme,the adrenal glands may produce too little cortisol and/or aldosterone and too much androgen. According to the National Institute of Health The classic (most severe) form of CAH affects 1 in 15,000 births worldwide. The nonclassic or mild form of CAH occurs affects 1 in 1,000 births worldwide.
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